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PTP Inhibitor I
CAS No. 2491-38-5
PTP Inhibitor I ( —— )
产品货号. M18306 CAS No. 2491-38-5
PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with a Ki value of 43 μM and PTP1B with a Ki value of 42 μM.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ￥446 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PTP Inhibitor I
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with a Ki value of 43 μM and PTP1B with a Ki value of 42 μM.
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产品描述PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with a Ki value of 43 μM and PTP1B with a Ki value of 42 μM. SHP-1 and PTP1B both have known roles in regulating insulin signaling as well as myeloid and lymphoid cell differentiation, making inhibitors of these phosphatases of interest in diabetes, cancer, allergy, and inflammation research.
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同义词——
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通路Others
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靶点Other Targets
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受体PTP
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研究领域——
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适应症——
化学信息
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CAS Number2491-38-5
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分子量215.04
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分子式C8H7BrO2
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纯度98%
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溶解度——
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SMILESOc1ccc(cc1)C(=O)CBr
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Arabaci, G., et al. αHaloacetophenone derivatives as photoreversible covalent inhibitors of protein tyrosine phosphatases. Journal of the American Chemical Society 121(21), 5085-5086 (1999).
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